Publications    

 
Anti-HER3 domain 1 and 3 antibodies reduce tumor growth by hindering HER2/HER3 dimerization and AKT-induced MDM2, XIAP and FoxO1 phosphorylation

Neoplasia 2013, Vol.15, N°3, 335-347. PMID: 23479511

Yassamine Lazrek^a,b, Olivier Dubreuil^b, Véronique Garambois^a, Nadège Gaborit^a,*, Gaelle Thomas^a, Christel Larbouret^a, Martine Pugnière^a, Corinne Henriquet^a, N. Vié^a, Bruno Robert^a, Céline Monnet^b, Khalid Bouayadi^b, Hakim Kharrat^b, Philippe Mondon^b, André Pèlegrin^a, Thierry Chardès<sup>a,**

a</sup>IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, F-34298, France ; INSERM, Unit 896, Montpellier, F-34298, France; Université Montpellier1, Montpellier, F-34298, France; CRLC Val d’Aurelle Paul Lamarque, Montpellier, F-34298, France;
^bMillegen SA, Immeuble BIOSTEP, 436 Rue Pierre et Marie Curie F-31670, Labège, France

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Affinity maturation of antibodies: optimized methods to generate high-quality scFv libraries and isolate IgG candidates by high-throughput screening.

Methods Mol Biol 2012, 907:451-61. PMID: 22907368

Renaut L, Monnet C, Dubreuil O, Zaki O, Bouayadi K and Kharrat H, Mondon P

MilleGen SA, Immeuble Biostep-Bat A, rue Pierre et Marie Curie, BP 38183, 31681 Labège cedex, France

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Mutagen: a random mutagenesis method providing a complementary diversity generated by human error-prone DNA polymerases.

Methods Mol Biol 2010, 634:373-386. PMID: 20676997

Mondon P, Grand D, Souyris N, Emond S, Bouayadi K and Kharrat H, 

MilleGen SA, Immeuble Biostep-Bat A, rue Pierre et Marie Curie, BP 38183, 31681 Labège cedex, France

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Alternative-splicing-based bicistronic vectors for ratio-controlled protein expression and application to recombinant antibody production.

Nucleic Acids Res 2009, Nov;37(20):e134. Epub 2009 Sep 3. PMID: 19729510

Fallot S ^1,2,3, Ben Naya R^1,3, Hieblot C ^1,3, Mondon P², Lacazette E^1,3, Bouayadi K², Kharrat A², Touriol C^1,3, Prats P<sup>1,3

1</sup>INSERM, U858, CHU Rangueil, Toulouse, France
² MilleGen SA, France
³Université Toulouse III Paul-Sabatier, Institut de Médecine Moléculaire de Rangueil, Equipe n°15, IFR31, Toulouse, France

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A cytoplasmic protein/protein interaction (CPPI) detection method based on reporter translation.

Anal.Biochem. 2009,384:362-364. PMID: 18977194

Renaut L, Bouayadi K, Kharrat H and Mondon P.

MilleGen SA, France

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Combinatorial engineering to enhance thermostability of amylosucrase.
 
Protein Sci. 2008, 17(6):967-976. PMID:18441231
 
Emond S^1,2, André I¹, Jaziri K¹, Potocki-Veronese G¹, Mondon P², Bouayadi K², Kharrat H², Monsan P¹ , Remaud.Simeon M¹.
 
¹ Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés (LISBP),  INSA, Toulouse  France.

² MilleGen SA,  Labège,  France

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A novel random mutagenesis approach using human mutagenic DNA polymerases to generate enzyme variant libraries.
 
Protein Eng. Des. Sel. 2008, 21(4):267-274. PMID:18287177
 
Emond S^1,2, Mondon P², Pizzut-Serrin S¹ , Douchy L², Crozet F², Bouayadi K², Kharrat H², Potocki-Veronese G¹ , Monsan P¹ , Remaud.Simeon M¹.
 
¹ Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés (LISBP),  INSA, Toulouse, France.

² MilleGen SA,  Labège, France

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Human antibody libraries: A race to engineer and explore a larger diversity.
 
Front. Biosci. 2008, 13:1117-1129. PMID: 17981617 
 
Mondon P, Dubreuil O, Bouayadi K and Kharrat H.
 
MilleGen SA,  Labège, France.

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Optimized and automated protocols for high throughput screening of amylosucrase libraries.   J. Biomol. Screen. 2007, 12(5):715-723. PMID: 17517906   Stéphane Emond1,2, Gabrielle Potocki-Véronèse1, Philippe Mondon2, Khalil Bouayadi2, Hakim Kharrat2, Pierre Monsan1 and Magali Remaud-Simeon1.   1 Laboratoire Biotechnologie-Bioprocédés, UMR CNRS 5504, UMR INRA 792, INSA, Toulouse, France. 2 MilleGen SA, Labège, France

Method for generation of human hyperdiversified antibody fragment library.   Biotechnol. J. 2007, 2:76-82. PMID: 17225253   Mondon P, Souyris N, Douchy L, Crozet F, Bouayadi K and Kharrat H.   MilleGen SA, Labège, France

Translational induction of VEGF Internal ribosome entry site elements during the early response to ischemic stress. Circ Res. 2007 Feb 16;100(3):305-8. PMID: 17255526 Bornes S*, Prado-Lourenco L*,•, Bastide A*, Zanibellato C*, Iacovoni JS*, Lacazette E*,  Prats AC*, Touriol C*, Prats H* *INSERM P U858, Université Paul Sabatier, Toulouse, France • MilleGen SA, Labège, France

Access to 2006 Publications

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Access to 2004-2005 Publications

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