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Antibody Discovery    

New generation of Fully Human Monoclonal Antibody Library: MG-Umab library

MilleGen has genetically engineered human recombinant antibody libraries with high complexity (Mondon et al, Biotechnology J. 2007, 2:76-82. PMID: 17225253 and patent WO2007137616).

In addition, a proofreading process has enriched the library with open reading frame (ORF) antibody sequences and improved the library quality selecting soluble antibodies. This new generation of library of 3.4 billion clones is one of the best optimized quality library on the market  with 94 % of clones encoding full-length antibodies. The high rate of functional antibodies allows a rapid and successful screening in order to provide an even wider range of promising antibody drug candidates per target.

  • Proprietary fully-human antibody library: MG-Umab library
  • mAb selection possible against most human targets even highly homologous to mouse (no immune tolerance in vitro)
  • Fully human antibodies, no need for further humanization
  • Optimized quality, validated on several targets
  • Expertise in large antibody library selection
  • Antibody screening based on biological activities
  • Integrated BioInformatic Platform for Data storage & Mining